Flux Expulsion - Field Evolution in Neutron Stars

Models for the evolution of magnetic fields of neutron stars are constructed, assuming the field is embedded in the proton superconducting core of the star. The rate of expulsion of the magnetic flux out of the core, or equivalently the velocity of outward motion of flux-carrying proton-vortices is determined from a solution of the Magnus equation of motion for these vortices. A force due to the pinning interaction between the proton-vortices and the neutron-superfluid vortices is also taken into account in addition to the other more conventional forces acting on the proton-vortices. Alternative models for the field evolution are considered based on the different possibilities discussed for the effective values of the various forces. The coupled spin and magnetic evolution of single pulsars as well as those processed in low-mass binary systems are computed, for each of the models. The predicted lifetimes of active pulsars, field strengths of the very old neutron stars, and distribution of the magnetic fields versus orbital periods in low-mass binary pulsars are used to test the adopted field decay models. Contrary to the earlier claims, the buoyancy is argued to be the dominant driving cause of the flux expulsion, for the single as well as the binary neutron stars. However, the pinning is also found to play a crucial role which is necessary to account for the observed low field binary and millisecond pulsars.Comment: 23 pages, + 7 figures, accepted for publication in Ap

Wieldy Finger and Hand Motion Detection for Human Computer Interaction

We have developed a gesture based interface for human computer interaction under the research field of computer vision.Earlier system have used the costlier system devices to make an effective interaction with systems, instead we have worked on the web cam based gesture input system.Our goal was to propound lesser cost, wieldy, object detection technique using blobs for detection of fingers.And to give number of count of the same.In addition, we have also implemented the hand gesture recognition

Novel 5-oxo-hexahydroquinoline derivatives: design, synthesis, in vitro P-glycoprotein-mediated multidrug resistance reversal profile and molecular dynamics simulation study

Overexpression of the efflux pump P-glycoprotein (P-gp) is one of the important mechanisms of multidrug resistance (MDR) in many tumor cells. In this study, 26 novel 5-oxo-hexahydroquinoline derivatives containing different nitrophenyl moieties at C-4 and various carboxamide substituents at C-3 were designed, synthesized and evaluated for their ability to inhibit P-gp by measuring the amount of rhodamine 123 (Rh123) accumulation in uterine sarcoma cells that overexpress P-gp (MES-SA/Dx5) using flow cytometry. The effect of compounds with highest MDR reversal activities was further evaluated by measuring the alterations of MES-SA/Dx5 cells' sensitivity to doxorubicin (DXR) using MTT assay. The results of both biological assays indicated that compounds bearing 2-nitrophenyl at C-4 position and compounds with 4-chlorophenyl carboxamide at C-3 demonstrated the highest activities in resistant cells, while they were devoid of any effect in parental nonresistant MES-SA cells. One of the active derivatives, 5c, significantly increased intracellular Rh123 at 100 mu M, and it also significantly reduced the IC50 of DXR by 70.1% and 88.7% at 10 and 25 mu M, respectively, in MES-SA/Dx5 cells. The toxicity of synthesized compounds against HEK293 as a noncancer cell line was also investigated. All tested derivatives except for 2c compound showed no cytotoxicity. A molecular dynamics simulation study was also performed to investigate the possible binding site of 5c in complex with human P-gp, which showed that this compound formed 11 average H-bonds with Ser909, Thr911, Arg547, Arg543 and Ser474 residues of P-gp. A good agreement was found between the results of the computational and experimental studies. The findings of this study show that some 5-oxo-hexahydroquinoline derivatives could serve as promising candidates for the discovery of new agents for P-gp-mediated MDR reversal

Fast determination of bisphenol A in spiked juice and drinking water samples by pipette tip solid phase extraction using cobalt metal organic framework as sorbent

A cobalt metal organic framework was prepared with rapid ultrasound assisted method by treatment of cobalt nitrate with pyridine 2,6-dicarboxilic acid dissolved in ethanolic media and used as a sorbent for pipette tip solid phase extraction of Bisphenol A (BPA) and its determination in spiked juice and drinking water samples by HPLC. Parameters which influence extraction efficiency such as pH, sample volume, amount of sorbent, type and volume of eluent, and number of draw/eject cycles for extraction and elusion were tested and optimized. Results showed that best extraction efficiency could be obtained at pH 3, 150 ‎µL of sample volume, 3 mg of adsorbent and 10 ‎µL of methanol as elution solvent. Numbers of draw/eject cycles for both sample extraction and elution were 7 cycles. Limit of detection and limit of quantification of this method were 0.07 and 0.3 µg L-1, respectively, with linear dynamic range of 0.3 to 300 µg L-1 for BPA. This method was applied successfully for determination of BPA in five spiked juices and drinking water samples.               KEY WORDS: Cobalt metal organic framework, Bisphenol A, Pipette-tip solid phase extraction, Juice analysis Bull. Chem. Soc. Ethiop. 2018, 32(3), 595-602.DOI: https://dx.doi.org/10.4314/bcse.v32i3.1

Diffusive transport of light in three-dimensional disordered Voronoi structures

The origin of diffusive transport of light in dry foams is still under debate. In this paper, we consider the random walks of photons as they are reflected or transmitted by liquid films according to the rules of ray optics. The foams are approximately modeled by three-dimensional Voronoi tessellations with varying degree of disorder. We study two cases: a constant intensity reflectance and the reflectance of thin films. Especially in the second case, we find that in the experimentally important regime for the film thicknesses, the transport-mean-free path does not significantly depend on the topological and geometrical disorder of the Voronoi foams including the periodic Kelvin foam. This may indicate that the detailed structure of foams is not crucial for understanding the diffusive transport of light. Furthermore, our theoretical values for transport-mean-free path fall in the same range as the experimental values observed in dry foams. One can therefore argue that liquid films contribute substantially to the diffusive transport of light in {dry} foams.Comment: 8 pages, 8 figure

Petrography, geochemistry and tectonic significance of the Mahoor granitoids (Lut Block, Eastern Iran)

The Mahoor granitoids are Cu–Zn-bearing porphyries that outcrop in the central part of the Lut Block, about 135 km south-west of Nehbandan (eastern Iran). These granitoids occur mainly as dykes and stocks that intrude Eocene volcanics. Petrographically, all the studied intrusives display porphyritic textures with mm-sized phenocrysts, most commonly of plagioclase and hornblende, embedded in a fine-grained groundmass with variable amounts of plagioclase, hornblende, clinopyroxene, quartz and opaques. Hydrothermal alteration affected these granitoids, as revealed by the common occurrence of sericite, chlorite, sphene/leucoxene, epidote and calcite. Chemical classification criteria show that the intrusives may be named as gabbrodiorites, diorites, monzodiorites and tonalites. Major element geochemistry reveals that all the studied lithologies are typically metaluminous (A/CNK ≤ 0.94) and, in addition, suggest, that they constitute a suite belonging to the high-K calc-alkaline series. Magnetic susceptibility (1485 × 10-5 SI) together with mineralogical and geochemical features show that they belong to magnetite granitoid series (I-type). In primitive mantle-normalized trace element spiderdiagrams, the analysed samples display strong enrichment in LILE compared to HFSE (15.5 ≤ RbN/YN ≤ 45.9), accompanied by negative anomalies of Nb, Ta and Ti. REE chondrite-normalized plots show slight to moderate LREE enrichment (4.9 ≤ LaN/LuN ≤ 8.4) and negative Eu anomalies (Eu/Eu* ratios vary from 0.65 to 0.88). Tectonic characteristics also indicate that the study area is emplaced in a volcanic arc setting. The whole set of geochemical data suggest that the Mahoor granitoids are co-genetic, belong to the calc-alkaline series and have been originated in an active continental margin setting. Sulfide mineralizations (pyrite, chalcopyrite and sphalerite) related to these granitoids are common and occur both disseminated and as hydrothermal veins, indicating a high mineralization potential for this area

The elusiveness of old neutron stars

Old neutron stars (ONSs) which have radiated away their internal and rotational energy may still shine if accreting the interstellar medium. Despite their large number, only two promising candidates have been detected so far and rather stringent limits on their observability follow from the analysis of ROSAT surveys. This contrasts with optimistic theoretical estimates that predicted a large number of sources in ROSAT fields. We have reconsidered the issue of ONSs observability, accounting for the spin and magnetic field evolution over the neutron star lifetime. In the framework of a spin-induced field decay model, we show that the total number of ONSs which are, at present, in the accretion stage is reduced by a factor ~5 over previous figures if the characteristic timescale for crustal current dissipation is ~ 10^8 - 10^9 yr. This brings theoretical predictions much closer to observational limits. Most ONSs should be at present in the propeller phase and, if subject to episodic flaring, they could be observable.Comment: 10 pages Latex, 5 ps figures. To be formatted with the AASTeX package. Accepted for publication in Ap

Successful use of axonal transport for drug delivery by synthetic molecular vehicles

We report the use of axonal transport to achieve intraneural drug delivery. We constructed a novel tripartite complex of an axonal transport facilitator conjugated to a linker molecule bearing up to a hundred reversibly attached drug molecules. The complex efficiently enters nerve terminals after intramuscular or intradermal administration and travels within axonal processes to neuron cell bodies. The tripartite agent provided 100-fold amplification of saturable neural uptake events, delivering multiple drug molecules per complex. _In vivo_, analgesic drug delivery to systemic and to non-targeted neural tissues was greatly reduced compared to existing routes of administration, thus exemplifying the possibility of specific nerve root targeting and effectively increasing the potency of the candidate drug gabapentin 300-fold relative to oral administration

Numerical Simulation of the Performance and Emission of a Diesel Engine with Diesel-biodiesel Mixture

IntroductionIncreasing industrialization, growing energy demand, limited reserves of fossil fuels, and increasing environmental pollution have jointly necessitated for exploration of a substitute for conventional liquid fuels. Vegetable oils can be used as alternatives to petroleum fuels for engine operation. These oils are mixtures of free-fatty acid molecules to contain carbon, hydrogen, and oxygen atoms. The ability to simulate the process of converting chemical energy to heat, energy users of computational fluid dynamics software in the design, analysis, and optimization of high-tech tools. Also, simulation saves time and reduces costs, workforce, and the space required.Materials and MethodsIn this research, a one-dimensional computational fluid dynamics solution with GT-Power software was used to simulate a four-cylinder, four-stroke, direct injection diesel engine to study the performance and exhaust emissions characteristics with different speeds and blends at full load. The engine speeds were chosen to be 1100 to 1400 rpm at an interval of 100 rpm. Also, fuel blends such as diesel (as a base), B5, and B10 biodiesel were selected for engine testing. To model a engine, we should have the dimensions of the engine, input air collection, output gases collection, the amount of sprinkled fuel, valves properties, combustion, and some of the estimates corresponding to the cylinder’s thermodynamic parameters when opening the output and input gate and to exchange the heat inside the cylinder as the input data. The model mainly consisted of an air cleaner, intake valve, exhaust valve, intake and exhaust port, injection nozzle, engine cylinder, and engine. Engine cylinder’s intake and exhaust ports are modeled geometrically with pipes. Before this investigation was carried out, a validation model for evaluation was done by experimental and simulation data. The validation results showed that the software model error is acceptable.Results and DiscussionThe engine performance and emissions were evaluated in terms of engine torque, specific fuel consumption, NOx, and CO emission at different engine speeds and fuels at full load. The results showed that with increasing the engine speeds, torque increased. On the other hand, the maximum engine torque for the diesel engine is slightly lower than the biodiesel-blended that increased by 4.4% because of the higher density and viscosity of biodiesel than diesel. Specific Fuel Consumption (SFC) is a measure of the fuel efficiency of any prime mover that burns fuel and produces rotation, or shaft, power. The results indicated that by increasing engine speeds, the SFC increased. A fuel with a lower heating value should be injected with more mass into the engine. This will increase the SFC. So, the maximum engine SFC for the diesel engine is more than the biodiesel-blended that decreased by 4.45% because of better fuel combustion and more power generation of biodiesel than diesel. The only nitrogen oxide that can be formed in an engine combustion temperature is nitrogen monoxide (NO). This pollutant factor can be converted to nitrogen dioxide (NO2) over the time of exhaust gas. The results showed that with increasing the engine speeds, the NOX emissions decrease steadily and then increases, which is due to the high temperature in the cylinder. The viscosity and density of fuels have an effect on NOX emission, and because of the larger droplets of the fuel, it released NOX. The highest NOx emissions belong B10 biodiesel in 1400 rpm, due to the high oxygen content of this fuel and the lowest NOx emissions belong B10 biodiesel in 1300 rpm, due to the low density of the fuel compared to diesel. CO is a colorless and odorless gas, whose even very low concentrations are dangerous for humans and animals. The results showed that with increasing the engine speeds, the CO emission decreased and the minimum CO emission for diesel engine is more than the biodiesel-blended that decreased by 37.61% because of excess oxygen availability and complete combustion in biodiesel than diesel.ConclusionThe results of this study showed that the B10 blend in high engine speeds, generally had the best performance and emissions characteristics among the three fuels used in this study. Also, this investigation will assist in the development of WCO biodiesel as a viable sustainable fuel source through the use of a CFD model, optimized engine configuration, and technical report